A Fatal Case of Serotonin Syndrome after Combined Moclobemide-Citalopram Intoxication
نویسندگان
چکیده
منابع مشابه
Fatal serotonin toxicity caused by moclobemide and fluoxetine overdose.
Both moclobemide and fluoxetine are used in the treatment of depression, and have been shown to produce fewer side effects than conventional tricyclic antidepressants. A combination of moclobemide and fluoxetine has been used in refractory depression, however there is potential for severe serotonin toxicity. We describe a lethal case of serotonin toxicity in a 36 year-old woman after she ingest...
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A 77-year-old female with recurrent non-small-cell lung cancer presented to a hospital outpatient clinic with tremor, weakness, inability to coordinate motor movements, and confusion. It was suspected that the symptoms were due to possible central nervous system metastases; however, a CT scan of her head was unremarkable. The lung clinic liaison pharmacist took a medication history from the pat...
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SEROTONIN SYNDROME CAUSED BY MOCLOBEMIDE – CLOMIPRAMIN INTERACTION The serotonin syndrome is due to serotoninergic hyperstimulation, which is caused, mostly, by the interaction between a serotoninergic agent and a serotonin-enhancing drug, in particular the monoaminooxidase inhibitors. A male patient, 21 years old, with presenting symptoms and findings as unconsciousness, flushing, diaphoresis,...
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Serotonin syndrome, a triad of autonomic instability, altered mental status and neuromuscular abnormalities, is usually attributed to serotonergic overdoses. Moclobemide is a new selective monoamine oxidase inhibitor (MAOI) that generally causes mild, self-limited gastrointestinal and central nervous system effects after ingestion. We present a case of serotonin syndrome that occurred after moc...
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A death caused by a new designer drug, 4-methylmethcathinone (mephedrone), is reported. Eight small plastic bags containing white powder were found in the jacket of a young dead male. Spot tests conducted by the police officer indicated the presence of 4-bromo-2,5-dimethoxyphenethylamine (2C-B) in the powders. Laboratory routine screening analyses of blood and vitreous humor did not reveal any ...
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ژورنال
عنوان ژورنال: Journal of Analytical Toxicology
سال: 2001
ISSN: 0146-4760,1945-2403
DOI: 10.1093/jat/25.2.147